Promising opportunities to improve polio vaccines
نویسندگان
چکیده
Polioviruses belong to Enterovirus C species and cause severe lesions of the nervous system. In post-polio eradication era, World Health Organisation recommends inactivated polio vaccines for effective long-term protection population. order meet needs global health, it is planned increase use traditional optimised introduce new types that are being developed based on current understanding RNA-containing viruses. The aim study was analyse ways improving vaccine preparations review promising areas immunoprophylaxis development. authors considered innovations across all stages technological process, aimed at obtaining vaccines, as well delivery systems. article presents information strains cell lines production. summarised results clinical studies genetically stable poliovirus, containing virus-like particles. most likely candidates introduction particles obtained from modified poliovirus. At moment, many issues related trends in poliomyelitis debatable need be addressed near future.
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ژورنال
عنوان ژورنال: ????????????. ????????????, ???????????, ???????
سال: 2022
ISSN: ['2221-996X', '2619-1156']
DOI: https://doi.org/10.30895/2221-996x-2022-22-2-336